Fast and accurate differential transcript usage by testing equivalence class counts

DRIMSeq: Dirichlet-multinomial framework for differential transcript usage and transcript usage QTL analyses in RNA-seq

Accurate, fast, and model-aware transcript expression quantification with Salmon

Existing methods for quantifying transcript abundance require a fundamental compromise: either use high quality read alignments and experiment-specific models or sacrifice them for speed. We introduce Salmon, a quantification method that overcomes this restriction by combining a novel ‘lightweight’ alignment procedure with a streaming parallel inference algorithm and a feature-rich bias model. ...

A rapid and accurate differential centrifugation method for platelet counts.

Bayesian estimation of differential transcript usage from RNA-seq data.

Next generation sequencing allows the identification of genes consisting of differentially expressed transcripts, a term which usually refers to changes in the overall expression level. A specific type of differential expression is differential transcript usage (DTU) and targets changes in the relative within gene expression of a transcript. The contribution of this paper is to: (a) extend the ...

Accurate automated leucocyte differential counts despite profound leucopenia.

The differential white cell counts produced by the Technicon H*1 Autoanalyser in profoundly leucopenic specimens were compared with those carried out by manual differential counting by light microscopy of peripheral blood smears stained with May-Grünwald-Giemsa stain. The correlation achieved allowed the H*1 derived differential count to be reported with confidence.